Sure! Yahoo!7 Games offers both single-player and multi-player games. Several multi-player games can also be played against computer opponents if you like.
Blackjack is played against the dealer, and if you don't want other "human" players at your table (and you're the host/creator of the table), then you can set the table type to "Private", preventing any new players from joining the table unless you invite them.
Pool can be played alone by selecting the "Training" option when you create a table.
Word Racer can also be played alone, although it's really designed to be a multi-player game. If you don't want other players at your table (and you're the host/creator of the table), then you can set the table type to “Private,” preventing any new players from joining the table unless you invite them.
Hearts, Euchre, Spades, Dominoes, Cribbage, Go Stop, and Chinese Checkers can be played against computer opponents (i.e., robots, bots, or AI).
To fill an empty seat with a computer "robot," select a table with open seats and click "Play Robot." You can also type "/auto" in the chat area to fill the empty seats with robots.